Reviews: 2023 Medicinal Chemistry Reviews

Ref. n°: REV2023

Volume :	58
Editor-In-Chief :	Joanne J. Bronson and Joachim Rudolph

Chapter 1	My Career in Medicinal Chemistry John A. Lowe III
Chapter 2	You Can’t Always Get What You Want. But If You Try Sometimes, You Get What You Need: Insights from My Unlikely Career in Drug Development Dennis Liotta
Chapter 3	5-HT2A Receptor as an Evolving Neurotherapeutic Target Andrew A. Bolinger, Noelle C. Anastasio, Kathryn A. Cunningham, Jia Zhou
Chapter 4	Recent Developments in the Discovery of Brain-Penetrant RIP1 Inhibitors Craig E. Stivala, Domagoj Vucic
Chapter 5	Advances Toward an Oral Non-Peptide Agonist of the GLP-1 Receptor Todd Fields, Eric Woerly, Michael G. Bell, Kyle W. Sloop, and Joseph D. Ho
Chapter 6	Recent Advances in Small-Molecule Inhibitors of Ketohexokinase (KHK) David Ebner, Gregory Tesz, and Kentaro Futatsugi
Chapter 7	Targeting Selective Tyrosine Kinase 2 (TYK2) Inhibitors for the Treatment of Autoimmune Diseases Silvana Leit, Bhaskar Srivastava, Nathan E. Genung, Joshua J. McElwee, Denise Levasseur, Scott D. Edmondson
Chapter 8	An Integrin Renaissance: Recent Progress of Integrin Modulators in the Clinic Darren Finkelstein, Timothy D. Machajewski
Chapter 9	Salt-inducible Kinases: An Emerging Target Class with Broad Therapeutic Potential Nicolas Desroy, Christophe Peixoto, Steve De Vos
Chapter 10	Small Molecule Degraders of Ikaros Zinc Finger (IKZF) Transcription Factors Natalie Holmberg-Douglas, Godwin K. Kumi, Ashok V. Purandare, Hunter Shunatona
Chapter 11	Recent Advances in Targeting the PRMT5/MTA Complex Christopher R. Smith, Matthew A. Marx
Chapter 12	Recent Advances in the Discovery of Cyclin-Dependent Kinase 2 (CDK2) Selective Inhibitors Kevin D. Freeman-Cook, Robert L. Hoffman
Chapter 13	Recent Advances in Synthetic Access to Antimicrobial Natural Products M. Alejandro Valdes-Pena and Joshua G. Pierce
Chapter 14	Practical Applications of Machine Learning for Anti-Infective Drug Discovery Nishant Sarkar and Jonathan M. Stokes
Chapter 15	Recent Progress in Antivirals against Zika Virus María-Jesús Pérez-Pérez, Eva-María Priego, Miguel A. Martín-Acebes
Chapter 16	Small Molecule RNA Splicing Modulators Hasane Ratnia, Kathleen D. McCarthy, Joseph L. Duffy, Sergey V. Paushkin, Sivaraman Dandapani
Chapter 17	Small-Molecule Modulators of Biomolecular Condensates George S. Tria, Joseph W. Tucker, Mary E. Spilker, Brooke A. Conti, Mariano Oppikofer
Chapter 18	The Rise, Fall, and Future Promise of IDO1 Inhibitors for Immuno-Oncology Emily Cherney, Susheel J. Nara, David Williams, Liping Zhang
Chapter 19	Drug-Induced Liver Injury: Mechanisms, Methods for Pre-Clinical Assessment and a Medicinal Chemist’s Perspective Anh T. Tran, James J. Crawford, Debashis Mandal, Tezcan Guney, Jamie Karmel
Chapter 20	Non-cyclic Dinucleotide STING Agonists for Immuno-Oncology Julian Lo, Emily Cherney
Chapter 21	Case History: Discovery and Development of Verquvo® (Vericiguat), a Soluble Guanylate Cyclase (sGC) Stimulator for the Treatment of Chronic Heart Failure Markus Follmann, Corina Becker, Lothar Roessig, Peter Sandner, and Johannes-Peter Stasch
Chapter 22	Case History: Corectim® (Delgocitinib), The First Topical JAK Inhibitor for The Treatment of Atopic Dermatitis Makoto Shiozaki
Chapter 23	New Chemical Entities Entering Phase III Trials in 2022 Matthew Condakes, Jennifer Jiang, David W. Lin, Rhiannon Thomas-Tran, Juan del Pozo, Christiana N. Teijaro
Chapter 24	To Market, to Market—2022: Small Molecules Erika Araujo, Ian M. Bell, Alexander Burckle, Dennis C. Koester, James R. Manning, Georgette Castanedo, Mingshuo Zeng, T. G. Murali Dhar, Natalie Holmberg-Douglas, Eric R. Welin, J. Robert Merritt, Kevin M. Peese, Joanne J. Bronson
Chapter 25	To Market, to Market—2022: Macromolecular Therapeutics Shion A. Lim, Nicholas J. Agard, Ryan L. Kelly, Benjamin N. Bell, Si-Jie Chen, Anna M. Gram, J. Robert Merritt, Ian Moench, Katarina Pance, Tatjana Petojevic

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Reviews: 2023 Medicinal Chemistry Reviews

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